Searchable abstracts of presentations at key conferences in endocrinology

ea0094oc7.6 | Thyroid | SFEBES2023

Shallow whole genome sequencing (swgs) as an aiding tool in monitoring of thyroid cancer

Jumaah Ali Al , Levy Miles , Reddy Narendra , Allsopp Rebecca , Page Karen , Shaw Jacqui , Gohil Shailesh

Introduction: Liquid biopsies have revolutionised cancer care, from accurate diagnosis to guiding treatment and surveillance. Here, we used shallow Whole Genome Sequencing (sWGS); a cost-effective and easy-to-perform test to explore concordance of copy number alterations (CNAs) between formalin-fixed paraffin-embedded (FFPE) tissue extracted DNA and circulating cell-free DNA (cfDNA) in patients with Thyroid Cancer (TC) during different stages of the disease. <...